Expression of atresia biomarkers in granulosa cells after. Atresia occurred during all stages of follicular development. In this process, a small group of primary follicles split from quiescent follicles in continuous streams either by atresia through apoptosis or conform the cohort of growing follicles. Read morphological characterization of the ovarian preantral follicle population of collared peccaries t ayassu tajacu l innaeus, 1758, anatomia, histologia, embryologia on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Growth and development of ovarian follicles require a series of coordinated events that induce morphological and functional changes within the follicle, leading to cell differentiation and oocyte development. The initiation of follicular atresia is orchestrated by the depletion of key survivalpromoting factors andor by specific death ligand molecules matsudaminehata et al. The preantral early antral follicle transition is the stage of follicular development during which gonadotropin dependence is obtained and the progression into growing or atresia of the follicle is made. Blockade of the ovarian cycle, with a massive previtellogenic follicular atresia, as a result of females isolation leads to conclude on the existence of sexual stimuli promoting vitellogenesis. The dried ovary was dissected and the cortex was maintained with approximately 1. A morphological and immunohistochemical study of healthy. Lower concentration of prl was associated with presence of pyknotic nuclei in granulosa cells which is an indicator of a late stage of cell death and follicular atresia 22, 67. Two forms of atresia types 1 and 2 were identified in vitellogenic follicles.
All of these structures have evolved for the primary functions of ovulation, fertilization of an ovum by a sperm, support of the developing embryo and fetus, and the birth and care of an infant. It has earlier been noted that higher concentration of prl in follicular fluid is positively correlated with early atresia. Oxytocin and estradiol concentrations in follicular fluid as a means for the classification of large bovine follicles. In granulosa cells, estradiol is produced by the aromatase under fsh and has various actions such as promoting folliculogenesis and inhibiting cell apoptosis see. Samples of goat ovarian cortex were cultured in vitro for 1 or 7 days in minimum essential medium control medium supplemented with different concentrations of. Introduction throughout ovarian development and function in mammals, a highly orchestrated, periodic. Female reproductive system an overview sciencedirect. The great mimicker march 2012, volume 198 number 3. A morphological and immunohistochemical study of healthy and. Teaching program for the students of the faculty of. Snap is expressed in mouse ovarian granulosa cells and. Ovarian follicular morphometry of south american fur seal. The balance between ovarian folliculogenesis and follicular atresia is critical for female fertility and is strictly regulated by a complex network of neuroendocrine and intraovarian signals.
In vitro studies have shown that igf1 synergizes with fsh to regulate the aromatase activity. The female reproductive system consists of the paired ovaries and oviducts, the uterus, the vagina, the external genitalia, and the mammary glands. We have not yet put together a complete index of the duke slide collection, but that is in the works. The processes of ovarian regression and follicular atresia which reproduction was. Pleiotropic effects of alphasnap m105i mutation on oocyte. The igf1 receptor has been localized in bovine oocytes, cumulus cells and in both granulosa and theca cells yoshida et al.
Female reproductive system an overview sciencedirect topics. For now, you may use the links below to at least browse the collections of aperioformatted digital slides directly on the servers. An essential binomial for ovarian development fernando ivan floresperez cesar rosasvelasco martha c. Original article the immunohistochemical localization of. The preantral early antral follicle transition is the stage of follicular development during which gonadotropin dependence is obtained and the progression into growing or atresia of the. Ovary follicle atresia an overview sciencedirect topics. Occurrence and significance of ovarian and follicular. Pseudoplatystoma fasciatum, regressao ovariana, foliculo atresico, histologia. Foley, in fundamentals of toxicologic pathology third edition, 2018. Biology and biotechnology of follicle development europe.
The objectives of this chapter are to equip the reader with the background for designing rigorous in vivo experiments, discerning and interpreting study. During the last decade many experiments have been performed to study the effects of growth hormone gh, somatotropin on reproductive functions. Atresia, the process of degeneration and removal of ovarian follicles from the ovary is an. Combelles 2 1university of new hampshire, department of molecular, cellular and biomedical sciences, durham nh, 2middlebury college, department of biology, middlebury vt, usa 1. Atresia is not limited to mature follicles, but may begin at any stage in follicular development.
Histology, embryology, cytology name and address of department. Strictly, the use of quantitative analysis of blood steroid hormones, as a method for predicting the maturation stage of southern hake, involves less handling of broodstock compared. Follicular atresia is a normal process in the ovary figure 26. Occurrence and significance of ovarian and follicular regression in cachara pseudoplatystoma fasciatum linnaeus, 1766. Abstract follicle atresia in mammals is a universal phenomenon characteristic by degenerative. Identification of potential biomarkers in donor cows for. Follicular atresia definition of follicular atresia by. Follicular atresia an overview sciencedirect topics. Identification of potential biomarkers in donor cows for in. Most of the studies found only slight or no effects of gh treatment, both on the oestrous cycle and on gonadotropin, progesterone, or oestrogen serum levels. This study investigated the effects of bone morphogenetic protein 6 bmp6 on in vitro primordial follicle development in goats. It has an association with biliary atresia and primary biliary cirrhosis.
Histological characterization of oocyte developmental stages. Intestinal obstruction is the common surgical problem in neonates of which intestinal atresia and stenosis contributes one third of cases. The ovaries from the control and experimental females, treated during one reproductive cycle or three cycles, were compared. The role of igf1 in the in vivo production of bovine.
The ovum pick upin vitro production opuivp of embryos is an advanced reproductive technology used in cattle production but the complex biological mechanisms behind ivp outcomes are not fully understood. The tissue was fractionated into small sections, some. Ovarian follicles are constituted by oocytes surrounded by follicular or granulosa cells whose development is modified during folliculogenesis. Histology of the ovary of chinchilla lanigera in captivity. Since the development of small preantral follicles is gonadotropin independent, an increase in atresia in these follicles is typically seen with directacting cytotoxic compounds. Pdf ovarian follicular development is an essential process in the determination of maturation stages. The female reproductive system is a complicated, hormonedependent group of tissues that may provide an interpretative challenge.
Effects of growth hormone on female reproductive organs. Picnotic nuclei and vacuoles as well as thickening of the basal membrane can. Samples of goat ovarian cortex were cultured in vitro for 1 or 7 days in minimum essential medium control medium supplemented with different concentrations of bmp6. Clinical diagnosis is difficult, and final diagnosis is generally made by histopathology. Changes in plasma steroid hormones and gonadal histology. Mar 20, 2006 atresia occurred during all stages of follicular development. Atretic follicles are evidenced because degenerative processes of the oocyte, the pellucid zone and the granulosa cells can be observed in them. In this study we sequenced rna of granulosa cells collected from holstein cows at oocyte aspiration prior to ivp, to identify candidate genes and biological mechanisms for favourable ivp. Bone morphogenetic protein6 bmp6 induces atresia in. Bone morphogenetic protein6 bmp6 induces atresia in goat. Pdf ovarian follicular development in the hawksbill turtle. Follicular atresia in ovaries of prochilodus lineatus.
Sep 18, 2017 the balance between ovarian folliculogenesis and follicular atresia is critical for female fertility and is strictly regulated by a complex network of neuroendocrine and intraovarian signals. Townson and others published ovarian follicular atresia find, read and cite all the research you need on researchgate. Follicular atresia is a degenerative process undergone by follicles that fail to reach complete maturation. Effects of igf1 in bovine ovarian follicular growth and oocyte quality. Aug 01, 20 read morphological characterization of the ovarian preantral follicle population of collared peccaries t ayassu tajacu l innaeus, 1758, anatomia, histologia, embryologia on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. During the reproductive period, primary follicles are formed cyclically in the ovary of teleost, which mature and are released at the ovulation time. Histologa, embriologa e ingeniera tisular bucodental. Histomorphological features of intestinal atresia and its. Follicular atresia occurs in all of the developing follicles that do not become the dominant follicle. Preantral follicles represent 95% of the follicular population and assisted reproductive technologies have been developed e. Follicular growth during this period is tightly regulated by oocytegranulosatheca cell interactions. Matriz extracelular tecido celulas matriz extracelular tecido epitelial poliedricas e justapostas pequena quantidade tecido conjuntivo fixas e migratorias abundante tecido muscular alongadas e contrateis quantidade moderada tecido nervoso com longos prolongamentos nenhuma prof.
Occurrence and significance of ovarian and follicular regression in. Histologia, embriologia e ingenieria tisular bucodental. Histological characterization of oocyte developmental. Histological characteristics of ovarian follicle atresia in dairy cows. Oct 01, 2001 during the last decade many experiments have been performed to study the effects of growth hormone gh, somatotropin on reproductive functions. Effect of oxytocin, ibmx and dbcamp on rabbit ovarian. The female reproductive system is composed of highly specialized organs which are in a state of constant change, from the sequential alterations characteristic of each menstrual cycle to the dramatic changes that occur during pregnancy.61 1224 1619 413 946 916 436 1382 670 1009 1434 233 504 481 572 671 947 1047 475 1386 574 450 579 1181 1258 360 1029 851 436 964 228 322 1418 59 1499 394 653 953 724 822 903 1365 1191 1447 870 970 1352 625 137